Article
Development of a new candidate H5N1 avian influenza virus for pre‐pandemic vaccine production
22 Oct 2009
Abstract excerpt
BACKGROUND: Highly pathogenic H5N1 avian influenza viruses currently circulating in birds have caused hundreds of human infections, and pose a significant pandemic threat. Vaccines are a major component of the public health preparedness for this likely event. The rapid evolution of H5N1 viruses has resulted in the emergence of multiple clades with distinct antigenic characteristics that require clade-specific...
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