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Article

Abnormal development of placenta in HtrA1-deficient mice.

Developmental biology - 1 Jan 2015

Hasan Md Zobaer, Ikawati Muthi, Tocharus Jiraporn, Kawaichi Masashi, Oka Chio

Abstract excerpt

Abnormal levels of High temperature requirement A1 (HtrA1) protein have been repeatedly observed in sera and placentas of preeclampsia patients. To understand the functions of HtrA1 in placentation and in the etiology of preeclampsia, we established HtrA1(-/-) mice. HtrA1(-/-) mice show intrauterine growth retardation, and their placentas are small due to a reduced size of the junctional zone and aberrant...

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Source

Identifiers

PMID: 25446274
DOI: 10.1016/j.ydbio.2014.10.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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