Article
Oxidant stress regulatory genetic variation in recipients and donors contributes to risk of primary graft dysfunction after lung transplantation.
The Journal of thoracic and cardiovascular surgery - 1 Feb 2015
Cantu Edward, Shah Rupal J, Lin Wei, Daye Zhongyin J, Diamond Joshua M, Suzuki Yoshikazu, Ellis John H, Borders Catherine F, Andah Gerald A, Beduhn Ben, Meyer Nuala J, Ruschefski Melanie, Aplenc Richard, Feng Rui, Christie Jason D
Abstract excerpt
OBJECTIVE: Oxidant stress pathway activation during ischemia reperfusion injury may contribute to the development of primary graft dysfunction (PGD) after lung transplantation. We hypothesized that oxidant stress gene variation in recipients and donors is associated with PGD. METHODS: Donors and recipients from the Lung Transplant Outcomes Group (LTOG) cohort were genotyped using the Illumina IBC chip filtered...
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