Article
Chronic central serous chorioretinopathy is associated with genetic variants implicated in age-related macular degeneration.
Ophthalmology - 1 Mar 2015
de Jong Eiko K, Breukink Myrte B, Schellevis Rosa L, Bakker Bjorn, Mohr Jacqueline K, Fauser Sascha, Keunen Jan E E, Hoyng Carel B, den Hollander Anneke I, Boon Camiel J F
Abstract excerpt
PURPOSE: In this study, single nucleotide polymorphisms (SNPs) at 19 loci, previously associated with age-related macular degeneration (AMD), were systematically tested for association in patients with chronic central serous chorioretinopathy (cCSC). In addition, we evaluated the effect of detailed phenotyping on these genetic associations. DESIGN: Case-control study. PARTICIPANTS: We included 292 cCSC patients,...
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