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Article

Investigating the genetic regulation of the ECF sigma factor σS in Staphylococcus aureus.

BMC microbiology - 30 Nov 2014

Burda Whittney N, Miller Halie K, Krute Christina N, Leighton Shane L, Carroll Ronan K, Shaw Lindsey N

Abstract excerpt

BACKGROUND: We previously identified an ECF sigma factor, σS, that is important in the stress and virulence response of Staphylococcus aureus. Transcriptional profiling of sigS revealed that it is differentially expressed in many laboratory and clinical isolates, suggesting the existence of regulatory networks that modulates its expression. RESULTS: To identify regulators of sigS, we performed a pull down assay...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25433799
DOI: 10.1186/s12866-014-0280-9
PMCID: PMC4265319

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