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A new staphylococcal sigma factor in the conserved gene cassette: functional significance and implication for the evolutionary processes

23 Jul 2003

Abstract excerpt

BACKGROUND: Staphylococcus aureus is a major human pathogen and causes a serious hospital infection due to the acquired multidrug resistance. Unlike the well-studied bacteria such as Escherichia coli and Bacillus subtilis, which have seven and 18 sigma factors, respectively, only two sigma factors have been known for S. aureus. We searched for possible sigma factor genes by examining the S. aureus genome with a...

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PMID: 12875655
DOI: 10.1046/j.1365-2443.2003.00668.x

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