Article
Natural genetic variation impacts expression levels of coding, non-coding, and antisense transcripts in fission yeast.
Molecular systems biology - 28 Nov 2014
Clément-Ziza Mathieu, Marsellach Francesc X, Codlin Sandra, Papadakis Manos A, Reinhardt Susanne, Rodríguez-López María, Martin Stuart, Marguerat Samuel, Schmidt Alexander, Lee Eunhye, Workman Christopher T, Bähler Jürg, Beyer Andreas
Abstract excerpt
Our current understanding of how natural genetic variation affects gene expression beyond well-annotated coding genes is still limited. The use of deep sequencing technologies for the study of expression quantitative trait loci (eQTLs) has the potential to close this gap. Here, we generated the first recombinant strain library for fission yeast and conducted an RNA-seq-based QTL study of the coding, non-coding,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.