Article
Methylation of the FGFR2 gene is associated with high birth weight centile in humans.
Epigenomics - 1 Jan 2014
Haworth Kim E, Farrell William E, Emes Richard D, Ismail Khaled M K, Carroll William D, Hubball Emma, Rooney Angela, Yates Alexandra M, Mein Charles, Fryer Anthony A
Abstract excerpt
AIMS: This study examined links between DNA methylation and birth weight centile (BWC), and explored the impact of genetic variation. MATERIALS & METHODS: Using HumanMethylation450 arrays, we examined candidate gene-associated CpGs in cord blood from newborns with low (<15th centile), medium (40-60th centile) and high (>85th centile) BWC (n = 12). Candidates were examined in an investigation cohort (n = 110)...
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