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Article

Transforming growth factor-beta 3 alters intestinal smooth muscle function: implications for gastroschisis-related intestinal dysfunction.

Digestive diseases and sciences - 1 May 2015

Moore-Olufemi S D, Olsen A B, Hook-Dufresne D M, Bandla V, Cox C S

Abstract excerpt

BACKGROUND: Gastroschisis (GS) is a congenital abdominal wall defect that results in the development of GS-related intestinal dysfunction (GRID). Transforming growth factor-β, a pro-inflammatory cytokine, has been shown to cause organ dysfunction through alterations in vascular and airway smooth muscle. The purpose of this study was to evaluate the effects of TGF-β3 on intestinal smooth muscle function and...

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Source

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Identifiers

PMID: 25431043
DOI: 10.1007/s10620-014-3439-1
PMCID: PMC4427617

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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