Profibrotic Changes Following Tension Application in a Fetal Lamb Model of Long Gap Esophageal Atresia

Abstract excerpt

<h4>Introduction</h4> Esophageal atresia is a common congenital anomaly, occurring in 1 in 3,500 live births. The Foker process has revolutionized the treatment of long gap esophageal atresia (LGEA). It is well established that the Foker process causes tension accelerated growth of the esophagus, but what occurs at the molecular level during tension accelerated growth is still unknown. We aimed to create tension...

Topics

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• Abnormalities, Multiple
• Chromosome Aberrations
• Congenital Diaphragmatic Hernia Studies
• Esophageal and GI Pathology
• Mutation
• Phenotype
• Tracheal and airway disorders
• Wound Healing and Treatments

Identifiers and source

Literature Corpus work

a7bbbdd8-0029-5d8a-b74f-3501e94c117b

DOI

10.64898/2026.01.26.701811