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Article

Intrauterine Growth Restriction Alters Mouse Intestinal Architecture during Development

8 Jan 2016

Abstract excerpt

Infants with intrauterine growth restriction (IUGR) are at increased risk for neonatal and lifelong morbidities affecting multiple organ systems including the intestinal tract. The underlying mechanisms for the risk to the intestine remain poorly understood. In this study, we tested the hypothesis that IUGR affects the development of goblet and Paneth cell lineages, thus compromising the innate immunity and...

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PMID: 26745886
DOI: 10.1371/journal.pone.0146542

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