Article
Association between estrogen receptora gene (ESR1) PvuII (T/C) and XbaI (A/G) polymorphisms and premature ovarian failure risk: evidence from a meta-analysis.
Journal of assisted reproduction and genetics - 1 Feb 2015
He Meirong, Shu Jingcheng, Huang Xing, Tang Hui
Abstract excerpt
BACKGROUND AND AIMS: Genetic factors are important in the pathogenesis of Premature ovarian failure (POF). Notably, estrogen receptor-a (ESR1) has been suggested as a possible candidate gene for POF; however, published studies of ESR1 gene polymorphisms have been hampered by small sample sizes and inconclusive or ambiguous results. The aim of this meta analysis is to investigate the associations between two novel...
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