Article
PvuII and XbaI in Estrogen Receptor 1 (ESR1) Polymorphisms and Susceptibility to Endometriosis Risk.
Clinical laboratory - 1 Aug 2020
Wang Jingwen, Hu Rong, Wang Jingjing, He Qian
Abstract excerpt
BACKGROUND: Studies have shown that variants in PvuII and XbaI loci are associated with the occurrence and progression of endometriosis (EM), while the results were in great debate. METHODS: A systematic review and meta-analysis were conducted to evaluate the role of PvuII and XbaI polymor-phisms in estrogen receptors (ESR1). The primary sources of the reviewed studies through December 2018, with restriction on...
Topics
- Case-Control Studies
- Endometriosis
- Estrogen Receptor alpha
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length