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Article

Exploiting high-throughput cell line drug screening studies to identify candidate therapeutic agents in head and neck cancer.

BMC pharmacology & toxicology - 27 Nov 2014

Nichols Anthony C, Black Morgan, Yoo John, Pinto Nicole, Fernandes Andrew, Haibe-Kains Benjamin, Boutros Paul C, Barrett John W

Abstract excerpt

BACKGROUND: There is an urgent need for better therapeutics in head and neck squamous cell cancer (HNSCC) to improve survival and decrease treatment morbidity. Recent advances in high-throughput drug screening techniques and next-generation sequencing have identified new therapeutic targets in other cancer types, but an HNSCC-specific study has not yet been carried out. We have exploited data from two large-scale...

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Source

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Identifiers

PMID: 25428177
DOI: 10.1186/2050-6511-15-66
PMCID: PMC4258049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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