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Article

Autoimmunity Links Vinculin to the Pathophysiology of Chronic Functional Bowel Changes Following Campylobacter jejuni Infection in a Rat Model.

Digestive diseases and sciences - 1 May 2015

Pimentel Mark, Morales Walter, Pokkunuri Venkata, Brikos Constantinos, Kim Sun Moon, Kim Seong Eun, Triantafyllou Konstantinos, Weitsman Stacy, Marsh Zachary, Marsh Emily, Chua Kathleen S, Srinivasan Shanthi, Barlow Gillian M, Chang Christopher

Abstract excerpt

BACKGROUND: Acute gastroenteritis can precipitate irritable bowel syndrome (IBS) in humans. Cytolethal distending toxin is common to all pathogens causing gastroenteritis. Its active subunit, CdtB, is associated with post-infectious bowel changes in a rat model of Campylobacter jejuni infection, including small intestinal bacterial overgrowth (SIBO). AIM: To evaluate the role of host antibodies to CdtB in...

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PMID: 25424202
DOI: 10.1007/s10620-014-3435-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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