Article
Interplay between 3'-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans.
BMC cancer - 25 Nov 2014
Jeon Young Joo, Kim Jong Woo, Park Hye Mi, Jang Hyo Geun, Kim Jung O, Oh Jisu, Chong So Young, Kwon Sung Won, Kim Eo Jin, Oh Doyeun, Kim Nam Keun
Abstract excerpt
BACKGROUND: Polymorphisms in angiogenesis-related genes and metabolic syndrome (MetS) risk factors play important roles in cancer development. Moreover, recent studies have reported associations between a number of 3'-UTR polymorphisms and a variety of cancers. The aim of this study was to investigate the associations of three VEGF 3'-UTR polymorphisms (1451C > T [rs3025040], 1612G > A [rs10434], and 1725G > A...
Topics
- 3' Untranslated Regions
- Asian People
- Case-Control Studies
- Colorectal Neoplasms
- Female