Transgenerational inheritance: how impacts to the epigenetic and genetic information of parents affect offspring health.

doi:10.1093/humupd/dmz017

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Article

Transgenerational inheritance: how impacts to the epigenetic and genetic information of parents affect offspring health.

Human reproduction update - 11 Sept 2019

Xavier Miguel João, Roman Shaun D, Aitken R John, Nixon Brett

Abstract excerpt

BACKGROUND: A defining feature of sexual reproduction is the transmission of genomic information from both parents to the offspring. There is now compelling evidence that the inheritance of such genetic information is accompanied by additional epigenetic marks, or stable heritable information that is not accounted for by variations in DNA sequence. The reversible nature of epigenetic marks coupled with multiple...

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Topics

Animals
Biological Evolution
DNA Methylation
Epigenesis, Genetic
Genome
Germ Cells
Heredity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Histone Code

Histones

Humans

Mammals

Mutation

Parents

Phenotype

Source

Open in PubMed

Identifiers

PMID: 31374565
DOI: 10.1093/humupd/dmz017

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