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Mycobacterium tuberculosis Pili Promote Adhesion to and Invasion of THP-1 Macrophages

1 Jan 2014

Abstract excerpt

Central to the paradigm of the pathogenesis of Mycobacterium tuberculosis is its ability to attach to, enter, and subsequently survive in host macrophages. However, little is known regarding the bacterial adhesins and invasins involved in this interaction with host macrophages. Pili are cell-surface structures produced by certain bacteria and have been implicated in adhesion to and invasion of phagocytes in...

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PMID: 25410564
DOI: 10.7883/yoken.67.476

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