Article
Mycobacterium tuberculosis produces pili during human infection.
Proceedings of the National Academy of Sciences of the United States of America - 20 Mar 2007
Alteri Christopher J, Xicohténcatl-Cortes Juan, Hess Sonja, Caballero-Olín Guillermo, Girón Jorge A, Friedman Richard L
Abstract excerpt
Mycobacterium tuberculosis is responsible for nearly 3 million human deaths worldwide every year. Understanding the mechanisms and bacterial factors responsible for the ability of M. tuberculosis to cause disease in humans is critical for the development of improved treatment strategies. Many bacterial pathogens use pili as adherence factors to colonize the host. We discovered that M. tuberculosis produces fine...
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