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Article

HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer

19 Nov 2014

Abstract excerpt

BACKGROUND: Worldwide, gastric cancer (GC) is the fourth most common malignancy and the most common cancer in East Asia. Development of targeted therapies for this disease has focused on a few known oncogenes but has had limited effects. OBJECTIVE: To determine oncogenic mechanisms and novel therapeutic targets specific for GC by identifying commonly dysregulated genes from the tumours of both Asian-Pacific and...

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Share to Metabolism, Diabetes, and Cancer
Share to Pancreatic function and diabetes
Share to Wnt/β-catenin signaling in development and cancer

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PMID: 25410163
DOI: 10.1136/gutjnl-2014-307918

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