Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunohistochemical characterization of the chemosensory pulmonary neuroepithelial bodies in the naked mole-rat reveals a unique adaptive phenotype.

PloS one - 1 Jan 2014

Pan Jie, Park Thomas J, Cutz Ernest, Yeger Herman

Abstract excerpt

The pulmonary neuroepithelial bodies (NEBs) constitute polymodal airway chemosensors for monitoring and signaling ambient gas concentrations (pO2, pCO2/H+) via complex innervation to the brain stem controlling breathing. NEBs produce the bioactive amine, serotonin (5-HT), and a variety of peptides with multiple effects on lung physiology and other organ systems. NEBs in mammals appear prominent and numerous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Carbon Dioxide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Adhesion

Share to Cell Proliferation

Share to Neurogenesis

Share to Neurosecretory Systems

Share to Oxygen

Source

Open in PubMed Open full text

Identifiers

PMID: 25409164
DOI: 10.1371/journal.pone.0112623
PMCID: PMC4237365

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunohistochemical characterization of the chemosensory pulmonary neuroepithelial bodies in the naked mole-rat reveals a unique adaptive phenotype.PMID 25409164Read ↗

Hyperplasia of pulmonary neuroendocrine cells in infancy and childhood.Semantic proximity Read ↗

More than one species of the naked mole-rat, a new biomedical model.Semantic proximity Read ↗

Pulmonary neuroendocrine cells function as airway sensors to control lung immune response.Semantic proximity Read ↗

Unique neurophysiologic characteristics of the longest-living rodent: the naked mole ratsSemantic proximity Read ↗

Characterizing the phenotype of pre-Bötzinger Complex neurons in rats.Semantic proximity Read ↗

Respiratory and autonomic dysfunction in congenital central hypoventilation syndromeSemantic proximity Read ↗

Transcriptome of neonatal preBötzinger complex neurones in Dbx1 reporter miceSemantic proximity Read ↗

<i>Phox2b</i> mutation mediated by <i>Atoh1</i> expression impaired respiratory rhythm and ventilatory responses to hypoxia and hypercapniaSemantic proximity Read ↗

Properties of subependymal cerebrospinal fluid contacting neurones in the dorsal vagal complex of the mouse brainstem.Semantic proximity Read ↗

Breathing with phox2b.Semantic proximity Read ↗

Cellular Basis of Pineal Gland Development: Emerging Role of Microglia as Phenotype Regulator.Semantic proximity Read ↗

Phenotypic traits of the hypothalamic PVN cells innervating airway-related vagal preganglionic neurons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.