Article
Inbreeding depression across the genome of Dutch Holstein Friesian dairy cattle.
Genetics, selection, evolution : GSE - 28 Oct 2020
Doekes Harmen P, Bijma Piter, Veerkamp Roel F, de Jong Gerben, Wientjes Yvonne C J, Windig Jack J
Abstract excerpt
BACKGROUND: Inbreeding depression refers to the decrease in mean performance due to inbreeding. Inbreeding depression is caused by an increase in homozygosity and reduced expression of (on average) favourable dominance effects. Dominance effects and allele frequencies differ across loci, and consequently inbreeding depression is expected to differ along the genome. In this study, we investigated differences in...
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