Article
Effects of sevoflurane on leucine-rich repeat kinase 2-associated Drosophila model of Parkinson's disease.
Molecular medicine reports - 1 Mar 2015
Shan Zhiming, Cai Song, Zhang Tao, Kuang Liting, Wang Qi, Xiu Huanhuan, Wen Jing, Gu Huaiyu, Xu Kangqing
Abstract excerpt
Patients with Parkinson's disease (PD) often require surgery, and therefore may receive inhalation anesthesia. However, it is currently unknown whether inhalation anesthetics affect the prognosis of the disease. Leucine‑rich repeat kinase 2 (LRRK2) genetic mutations are the most common cause of familial PD, contributing to ~39% of all cases in certain populations. The aim of the present study was to determine the...
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