Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA let-7a suppresses the growth and invasion of cholesteatoma keratinocytes

18 Nov 2014

Abstract excerpt

Cholesteatomas are benign epidermally‑derived lesions of the temporal bone that are caused by migration of hyperproliferative keratinocytes into the middle ear and mastoid cavity. The molecular mechanisms that regulate the pathogenesis of cholesteatomas are currently not fully understood. The present study demonstrated the antigrowth and anti‑invasive effects of let‑7a microRNA (miRNA) on cholesteatoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Ear Surgery and Otitis Media
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25405753
DOI: 10.3892/mmr.2014.2971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA let-7a suppresses the growth and invasion of cholesteatoma keratinocytesPMID 25405753Read ↗

Cholesteatoma Growth and ProliferationSemantic proximity Read ↗

Study of the miRNA expression profile of cholesteatoma-derived exosomes and its clinical applicationSemantic proximity Read ↗

MicroRNA-21 Overexpression Contributes to Vestibular Schwannoma Cell Proliferation and SurvivalSemantic proximity Read ↗

miRNA-7 Attenuation in Schwannoma Tumors Stimulates Growth by Upregulating Three Oncogenic Signaling PathwaysSemantic proximity Read ↗

Cholesteatoma-associated fibroblasts modulate epithelial growth and differentiation through KGF/FGF7 secretion.Semantic proximity Read ↗

Cleft Palate Induced by Mycophenolate Mofetil Is Associated with miR-4680-3p and Let-7c-5p in Human Palate CellsSemantic proximity Read ↗

MicroRNA-21 Affects Proliferation and Apoptosis by Regulating Expression of PTEN in Human Keloid FibroblastsSemantic proximity Read ↗

Inhibitory Effect of MicroRNA-34a on Retinal Pigment Epithelial Cell Proliferation and MigrationSemantic proximity Read ↗

miR‐483‐3p controls proliferation in wounded epithelial cellsSemantic proximity Read ↗

Immortalization of Normal Adult Human Middle Ear Epithelial Cells Using a Retrovirus Containing the E6/E7 Genes of Human Papillomavirus Type 16Semantic proximity Read ↗

PDGF-BB Enhances the Proliferation of Cells in Human Orbital Fibroblasts by Suppressing PDCD4 Expression Via Up-Regulation of microRNA-21Semantic proximity Read ↗

Sevoflurane inhibits the migration and invasion of glioma cells by upregulating microRNA-637Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.