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Article

Inhibitory Effect of MicroRNA-34a on Retinal Pigment Epithelial Cell Proliferation and Migration

22 Aug 2013

Abstract excerpt

PURPOSE: Retinal pigment epithelial (RPE) cells play important roles in ophthalmologic diseases such as proliferative vitreoretinopathy, AMD, and diabetic retinopathy. MicroRNA-34a (miR-34a) has been reported to be important in the regulation of cell proliferation, migration, differentiation, and apoptosis. In this study, we explored the effects of miR-34a on RPE cells. METHODS: The expression level of miR-34a in...

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PMID: 23970470
DOI: 10.1167/iovs.13-11873

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