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Article

Higher frequency of certain cancers in LRRK2 G2019S mutation carriers with Parkinson disease: a pooled analysis.

JAMA neurology - 1 Jan 2015

Agalliu Ilir, San Luciano Marta, Mirelman Anat, Giladi Nir, Waro Bjorg, Aasly Jan, Inzelberg Rivka, Hassin-Baer Sharon, Friedman Eitan, Ruiz-Martinez Javier, Marti-Masso Jose Felix, Orr-Urtreger Avi, Bressman Susan, Saunders-Pullman Rachel

Abstract excerpt

IMPORTANCE: Patients with Parkinson disease (PD) who harbor LRRK2 G2019S mutations may have increased risks of nonskin cancers. However, the results have been inconsistent across studies. OBJECTIVES: To analyze pooled data from 5 centers to further examine the association between LRRK2 G2019S mutation and cancer among patients with PD and to explore factors that could explain discrepancies. DESIGN, SETTING, AND...

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Identifiers

PMID: 25401981
DOI: 10.1001/jamaneurol.2014.1973
PMCID: PMC4366130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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