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Article

Frailty, mycophenolate reduction, and graft loss in kidney transplant recipients.

Transplantation - 1 Apr 2015

McAdams-DeMarco Mara A, Law Andrew, Tan Jingwen, Delp Cassandra, King Elizabeth A, Orandi Babak, Salter Megan, Alachkar Nada, Desai Niraj, Grams Morgan, Walston Jeremy, Segev Dorry L

Abstract excerpt

BACKGROUND: Mycophenolate mofetil (MMF) side effects often prompt dose reduction or discontinuation, and this MMF dose reduction (MDR) can lead to rejection and possibly graft loss. Unfortunately, little is known about what factors might cause or contribute to MDR. Frailty, a measure of physiologic reserve, is emerging as an important, novel domain of risk in kidney transplantation recipients. We hypothesized...

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PMID: 25393156
DOI: 10.1097/TP.0000000000000444
PMCID: PMC4382409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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