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Article

Association between insulin growth factor-1, bone mineral density, and frailty phenotype in children with chronic kidney disease.

Pediatric nephrology (Berlin, Germany) - 1 Jul 2021

Karava Vasiliki, Dotis John, Christoforidis Athanasios, Liakopoulos Vassilios, Kondou Antonia, Tsigaras Georgios, Tsioni Konstantina, Kollios Konstantinos, Printza Nikoleta

Abstract excerpt

BACKGROUND: This cohort study investigates the association between insulin growth factor-1 (IGF-1), bone mineral density, and frailty phenotype in children with chronic kidney disease (CKD). METHODS: Forty-six patients (median age 14.5 years) were prospectively enrolled. Frailty phenotype was defined as the presence ≥ 3 of the following indicators: suboptimal growth/weight gain (body mass index height age < 5th...

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Identifiers

PMID: 33598823
DOI: 10.1007/s00467-021-04918-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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