Article
Physiologic characterization of the chronic bronchitis phenotype in GOLD grade IB COPD.
Chest - 1 May 2015
Elbehairy Amany F, Raghavan Natya, Cheng Sicheng, Yang Ling, Webb Katherine A, Neder J Alberto, Guenette Jordan A, Mahmoud Mahmoud I, O'Donnell Denis E
Abstract excerpt
BACKGROUND: Smokers with persistent cough and sputum production (chronic bronchitis [CB]) represent a distinct clinical phenotype, consistently linked to negative clinical outcomes. However, the mechanistic link between physiologic impairment, dyspnea, and exercise intolerance in CB has not been studied, particularly in those with mild airway obstruction. We, therefore, compared physiologic abnormalities during...
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