The chronic bronchitis phenotype in chronic obstructive pulmonary disease: features and implications.

Abstract excerpt

PURPOSE OF REVIEW: Chronic obstructive pulmonary disease (COPD) is a major public health problem that is projected to rank fifth worldwide in terms of disease burden and third in terms of mortality. Chronic bronchitis is associated with multiple clinical consequences, including hastening lung function decline, increasing risk of exacerbations, reducing health-related quality of life, and possibly raising...

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