Article
Defining a phenotype of severe COPD patients who develop chronic hypercapnia.
Respiratory medicine - 1 Jan 2000
Boersma Renzo, Bakker Jens T, de Vries Maaike, Raveling Tim, Slebos Dirk-Jan, Wijkstra Peter J, Hartman Jorine E, Duiverman Marieke L
Abstract excerpt
INTRODUCTION: Chronic hypercapnia, defined by elevated blood CO2 levels, is a serious complication most prevalent in severe COPD. It negatively impacts quality of life, increases hospitalization rates, and elevates mortality risks. However, not all severe COPD patients develop chronic hypercapnia, and its underlying mechanisms remain unclear. Identifying clinical and pathophysiological predictors of hypercapnia...
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