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Article

Adaptive immunity is the primary force driving selection of equine infectious anemia virus envelope SU variants during acute infection.

Journal of virology - 1 Sept 2004

Mealey Robert H, Leib Steven R, Pownder Sarah L, McGuire Travis C

Abstract excerpt

Equine infectious anemia virus (EIAV) is a lentivirus that causes persistent infection in horses. The appearance of antigenically distinct viral variants during recurrent viremic episodes is thought to be due to adaptive immune selection pressure. To test this hypothesis, we evaluated envelope SU cloned sequences from five severe combined immunodeficient (SCID) foals infected with EIAV. Within the SU...

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Identifiers

PMID: 15308724
DOI: 10.1128/JVI.78.17.9295-9305.2004
PMCID: PMC506964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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