Article
Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease.
American journal of respiratory and critical care medicine - 15 Feb 2015
Kropski Jonathan A, Pritchett Jason M, Zoz Donald F, Crossno Peter F, Markin Cheryl, Garnett Errine T, Degryse Amber L, Mitchell Daphne B, Polosukhin Vasiliy V, Rickman Otis B, Choi Leena, Cheng Dong-Sheng, McConaha Melinda E, Jones Brittany R, Gleaves Linda A, McMahon Frank B, Worrell John A, Solus Joseph F, Ware Lorraine B, Lee Jae Woo, Massion Pierre P, Zaynagetdinov Rinat, White Eric S, Kurtis Jonathan D, Johnson Joyce E, Groshong Steve D, Lancaster Lisa H, Young Lisa R, Steele Mark P, Phillips Iii John A, Cogan Joy D, Loyd James E, Lawson William E, Blackwell Timothy S
Abstract excerpt
RATIONALE: Asymptomatic relatives of patients with familial interstitial pneumonia (FIP), the inherited form of idiopathic interstitial pneumonia, carry increased risk for developing interstitial lung disease. OBJECTIVES: Studying these at-risk individuals provides a unique opportunity to investigate early stages of FIP pathogenesis and develop predictive models of disease onset. METHODS: Seventy-five...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.