Article
Understanding Idiopathic Interstitial Pneumonia: A Gene-Based Review of Stressed Lungs.
BioMed research international - 1 Jan 2015
van Moorsel Coline H M, Hoffman Thijs W, van Batenburg Aernoud A, Klay Dymph, van der Vis Joanne J, Grutters Jan C
Abstract excerpt
Pulmonary fibrosis is the main cause of severe morbidity and mortality in idiopathic interstitial pneumonias (IIP). In the past years, there has been major progress in the discovery of genetic factors that contribute to disease. Genes with highly penetrant mutations or strongly predisposing common risk alleles have been identified in familial and sporadic IIP. This review summarizes genes harbouring causative...
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