Article

Altered Tonsillar Microbiome in Children with Down Syndrome and Obstructive Sleep Apnea

2026-06-01

Abstract excerpt

<h4>Background and Objectives</h4> Children with Down syndrome (DS) have a high prevalence of obstructive sleep apnea (OSA) due to anatomic, neuromuscular, immunological and metabolic factors, yet the contribution of the tonsillar microbiome to airway obstruction in this population remains unexplored. We hypothesized that DS-associated OSA would be associated with a distinct tonsillar microbiome compared to non-D...

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Literature Corpus work: cb50cb28-bded-56e2-b7fb-342817b07823
DOI: 10.64898/2026.05.29.728812

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