Article
Cross-species genetic exchange between visceral and cutaneous strains of Leishmania in the sand fly vector.
Proceedings of the National Academy of Sciences of the United States of America - 25 Nov 2014
Romano Audrey, Inbar Ehud, Debrabant Alain, Charmoy Melanie, Lawyer Phillip, Ribeiro-Gomes Flavia, Barhoumi Mourad, Grigg Michael, Shaik Jahangheer, Dobson Deborah, Beverley Stephen M, Sacks David L
Abstract excerpt
Genetic exchange between Leishmania major strains during their development in the sand fly vector has been experimentally shown. To investigate the possibility of genetic exchange between different Leishmania species, a cutaneous strain of L. major and a visceral strain of Leishmania infantum, each bearing a different drug-resistant marker, were used to coinfect Lutzomyia longipalpis sand flies. Eleven...
Topics
- Animals
- Insect Vectors
- Leishmania
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Polymorphism, Single Nucleotide
- Psychodidae
- Species Specificity