Article
A test for genetic exchange in mixed infections of Leishmania major in the sand fly Phlebotomus papatasi.
The Journal of protozoology - 1 Jan 2000
Panton L J, Tesh R B, Nadeau K C, Beverley S M
Abstract excerpt
We tested if genetic exchange was observable between two strains of Leishmania major (Trypanosomatidae) during mixed infection of the sand fly Phlebotomus papatasi. Previous studies suggested that genetic exchange may occur in natural populations of Leishmania at a low frequency, but experimental crosses examining small numbers of progeny (less than 60) did not reveal hybrid parasites. Accordingly, a strategy was...
Topics
- Animals
- Blotting, Southern
- DNA, Protozoan
- Drug Resistance
- Gene Amplification
- Genetic Markers
- Leishmania tropica
- Mutation
- Nucleic Acid Hybridization
- Phlebotomus
- Recombination, Genetic
