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Article

Extensive heterozygosity and genetic exchange among natural populations of Leishmania species.

Proceedings of the National Academy of Sciences of the United States of America - 21 Apr 2026

Alves-Ferreira Eliza V C, Barhoumi Mourad, Ferreira Tiago R, Brown Matthew W, Volf Petr, Saadi-BenAoun Yusr, Khammari Immen, Kherachi Ihcen, Fathallah Mili Akila, Harrat Zoubir, Guizani Ikram, Sacks David L, Lukeš Julius, Grigg Michael E

Abstract excerpt

Genetic hybridization within the genus Leishmania has been demonstrated experimentally, but the extent to which this occurs naturally among circulating populations remains enigmatic. The current consensus is that natural populations undergo preponderant clonal evolution, presumably expanding by asexual replication. To investigate the extent to which inter- and intraspecific genetic exchange has impacted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41996162
DOI: 10.1073/pnas.2537999123
PMCID: PMC13099610

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