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Article

Demonstration of genetic exchange during cyclical development of Leishmania in the sand fly vector.

Science (New York, N.Y.) - 10 Apr 2009

Akopyants Natalia S, Kimblin Nicola, Secundino Nagila, Patrick Rachel, Peters Nathan, Lawyer Phillip, Dobson Deborah E, Beverley Stephen M, Sacks David L

Abstract excerpt

Genetic exchange has not been shown to be a mechanism underlying the extensive diversity of Leishmania parasites. We report here evidence that the invertebrate stages of Leishmania are capable of having a sexual cycle consistent with a meiotic process like that described for African trypanosomes. Hybrid progeny were generated that bore full genomic complements from both parents, but kinetoplast DNA maxicircles...

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Identifiers

PMID: 19359589
DOI: 10.1126/science.1169464
PMCID: PMC2729066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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