Article
Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution.
Nature genetics - 1 Dec 2014
von Mentzer Astrid, Connor Thomas R, Wieler Lothar H, Semmler Torsten, Iguchi Atsushi, Thomson Nicholas R, Rasko David A, Joffre Enrique, Corander Jukka, Pickard Derek, Wiklund Gudrun, Svennerholm Ann-Mari, Sjöling Åsa, Dougan Gordon
Abstract excerpt
Enterotoxigenic Escherichia coli (ETEC), a major cause of infectious diarrhea, produce heat-stable and/or heat-labile enterotoxins and at least 25 different colonization factors that target the intestinal mucosa. The genes encoding the enterotoxins and most of the colonization factors are located on plasmids found across diverse E. coli serogroups. Whole-genome sequencing of a representative collection of ETEC...
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