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Article

Allele variants of enterotoxigenic Escherichia coli heat-labile toxin are globally transmitted and associated with colonization factors.

Journal of bacteriology - 1 Jan 2015

Joffré Enrique, von Mentzer Astrid, Abd El Ghany Moataz, Oezguen Numan, Savidge Tor, Dougan Gordon, Svennerholm Ann-Mari, Sjöling Åsa

Abstract excerpt

Enterotoxigenic Escherichia coli (ETEC) is a significant cause of morbidity and mortality in the developing world. ETEC-mediated diarrhea is orchestrated by heat-labile toxin (LT) and heat-stable toxins (STp and STh), acting in concert with a repertoire of more than 25 colonization factors (CFs). LT, the major virulence factor, induces fluid secretion after delivery of a monomeric ADP-ribosylase (LTA) and its...

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Source

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Identifiers

PMID: 25404692
DOI: 10.1128/JB.02050-14
PMCID: PMC4272596

Genes

LTA
LTB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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