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Insights into enterotoxigenic Escherichia coli diversity in Bangladesh utilizing genomic epidemiology.

Scientific reports - 13 Jun 2017

Sahl Jason W, Sistrunk Jeticia R, Baby Nabilah Ibnat, Begum Yasmin, Luo Qingwei, Sheikh Alaullah, Qadri Firdausi, Fleckenstein James M, Rasko David A

Abstract excerpt

Enterotoxigenic Escherichia coli (ETEC) cause more than 500,000 deaths each year in the developing world and are characterized on a molecular level by the presence of genes that encode the heat-stable (ST) and/or heat-labile (LT) enterotoxins, as well as surface structures, known as colonization factors (CFs). Genome sequencing and comparative genomic analyses of 94 previously uncharacterized ETEC isolates...

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Identifiers

PMID: 28611468
DOI: 10.1038/s41598-017-03631-x
PMCID: PMC5469772

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