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Article

The tumor suppressor rpl36 restrains KRAS(G12V)-induced pancreatic cancer.

Zebrafish - 1 Dec 2014

Provost Elayne, Bailey Jennifer M, Aldrugh Sumar, Liu Shu, Iacobuzio-Donahue Christine, Leach Steven D

Abstract excerpt

Ribosomal proteins are known to be required for proper assembly of mature ribosomes. Recent studies indicate an additional role for ribosomal proteins as candidate tumor suppressor genes. Pancreatic acinar cells, recently identified as effective cells of origin for pancreatic adenocarcinoma, display especially high-level expression of multiple ribosomal proteins. We, therefore, functionally interrogated the...

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Source

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Identifiers

PMID: 25380065
DOI: 10.1089/zeb.2014.1024
PMCID: PMC4248247

Genes

KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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