IL2-IL21 gene cluster polymorphism is not associated with allograft function after kidney transplantation.

doi:10.1007/s11255-014-0867-y

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Article

IL2-IL21 gene cluster polymorphism is not associated with allograft function after kidney transplantation.

International urology and nephrology - 1 Dec 2014

Kwiatkowska Ewa, Domanski Leszek, Kłoda Karolina, Pawlik Andrzej, Safranow Krzysztof, Ciechanowski Kazimierz

Abstract excerpt

BACKGROUND: Cytokines are key mediators of the immune response after transplantation. The interleukin (IL)-2 cytokine family, which includes IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, is of particular interest because of its importance in the allogenic response. The aim of this study was to examine the association between the rs6822844 gene polymorphism in the IL2-IL21 region and allograft function after kidney...

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PMID: 25377634
DOI: 10.1007/s11255-014-0867-y
PMCID: PMC4247846

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