Article
Association of the Smad3 and NFATc2 gene polymorphisms and their serum levels with susceptibility to rheumatoid arthritis in Polish cohorts.
Clinical and experimental immunology - 1 Mar 2015
Paradowska-Gorycka A, Romanowska-Próchnicka K, Haladyj E, Manczak M, Maslinski S, Olesinska M
Abstract excerpt
One among many factors involved in induction of rheumatoid arthritis (RA) are T cells, the differentiation of which depends upon a unique combination of stimulants and subsequent activation of diverse transcription factors. The aim of this study was to identify polymorphic variants in Smad3 and NFATc2 genes and their possible association with susceptibility to and severity of RA. A total of 272 RA patients, 321...
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