Role of ERK1/2 and p38 Protein Kinases in Tumors: Biological Insights and Clinical Implications

Abstract excerpt

Significant advancements have been achieved over recent decades in deciphering the molecular mechanisms driving malignant tumor development. Despite this progress, the precise roles of individual genes, their interactions, and the associated signaling pathways involved in tumor proliferation remain insufficiently characterized. Among these pathways, the mitogen-activated protein kinases (MAPKs) extracellular...

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