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Beclin 1 Biology and its Role in Heart Disease

14 May 2015

Abstract excerpt

Macroautophagy (hereafter termed autophagy) is a highly evolutionarily conserved pathway that degrades intracellular components such as damaged organelles in lysosome. Autophagy occurs at low basal levels in virtually all types of cells, which is required for the maintenance of cellular homeostasis. Beclin 1 protein, encoded by the beclin 1 gene, plays a central role in the regulation of autophagy. Beclin 1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25373623
DOI: 10.2174/1573403x10666141106104606

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