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Crosstalk of autophagy and ferroptosis in cardiovascular diseases: from pathophysiology to novel therapy

29 May 2025

Abstract excerpt

Cardiovascular diseases (CVDs) are characterized by high morbidity and mortality rates, imposing substantial epidemiological and economic burdens worldwide. Among the multifaceted mechanisms implicated in CVDs, autophagy and ferroptosis, two intimately linked cellular processes, emerge as pivotal pathophysiological contributors. Autophagy, as an evolutionary conserved process that mediates the degradation and...

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PMID: 40450834
DOI: 10.1016/j.redox.2025.103705

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