Article
It's a noisy business! Genetic regulation at the nanomolar scale.
Trends in genetics : TIG - 1 Feb 1999
McAdams H H, Arkin A
Abstract excerpt
Many molecules that control genetic regulatory circuits act at extremely low intracellular concentrations. Resultant fluctuations (noise) in reaction rates cause large random variation in rates of development, morphology and the instantaneous concentration of each molecular species in each cell. To achieve regulatory reliability in spite of this noise, cells use redundancy in genes as well as redundancy and...
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