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Article

-765 g>c polymorphism of the cox-2 gene and gastric cancer risk in Brazilian population.

Arquivos de gastroenterologia - 1 Jan 2000

Campanholo Vanessa Maria de Lima Pazine, Felipe Aledson Vitor, de Lima Jacqueline Miranda, Pimenta Célia Aparecida Marques, Ventura Rogéria Maria, Forones Nora Manoukian

Abstract excerpt

CONTEXT: Genomic alterations play important roles in gastric cancer carcinogenesis. Cyclooxygenases (COX) are important enzymes in the maintenance of mucosal integrity and in pathological processes, mainly in inflammation and cancer. The -765G>C COX-2 polymorphism has been implicated in gastric cancer risk. OBJECTIVES: To evaluate the COX-2 gene polymorphism as a predictor of gastric cancer risk. METHODS: One...

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PMID: 25003256
DOI: 10.1590/s0004-28032014000200002

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